CANADA BONE GRAFT AND SUBSTITUTE MARKET FORECAST 2023-2030

The Canada bone graft and substitute market segmentation includes application and type. The type segment includes synthetics and additives, autografts, and allografts. The synthetics and additives segment further includes polymer, ceramic, bone morphogenetic proteins, and composite.

Synthetic bone substitute materials are used to mitigate the risk of immune responses and health complications that can arise from natural materials. These man-made synthetic bone substitutes are engineered to mimic the biological properties of natural bone. They serve as synthetic alternatives to autogenous bone grafts in the context of craniofacial skeleton restoration and augmentation. Consequently, they have emerged as a significant preference in the arsenal of surgeons.

Ceramic-based bone grafts are widely utilized artificial products to reduce the reliance on bone grafts from the iliac crest. These ceramic matrices are composed of inorganic, ionically bonded formulations, encompassing a broad spectrum of bone graft substitutes. Ceramics, as a category, display notable diversity stemming from differences in their composition, manufacturing process, porosity, and structure. Various materials, such as calcium sulfate, hydroxyapatite, and tricalcium phosphate, are employed in the production of ceramic items. Each of these potential additives possesses distinct mechanical, bonding, and biodegradability properties.

A composite bone graft comprises various components employed in bone grafting surgeries. Generally, it incorporates an osteoconductive framework, which offers structural reinforcement for bone development, along with an osteogenic or osteoinductive substance that stimulates the creation of fresh bone tissue. This amalgamation boosts the graft’s capacity to foster bone rejuvenation and healing. Composite bone grafts are frequently utilized as substitutes for autografts, providing efficient options for a range of orthopedic and dental purposes.

Polymer-based bone grafts utilize both degradable and nondegradable polymers, either independently or in combination with other materials. For instance, open porosity polylactic acid polymer is an example of such a combination. Polylactic acid, polyglycolic acid, poly-caprolactone, along with their copolymers and derivatives, commonly referred to as aliphatic polyesters, are the polymers most frequently employed for the purpose of rejuvenating bone. Nickel-titanium accessories have also been explored in dentistry for bone rejuvenation due to their numerous desirable properties, which include strong mechanical strength, good biocompatibility, erosion resistance, and elastic modulus.

Bone morphogenetic protein (BMP) is a versatile growth factor that belongs to the transforming growth factor-beta (TGF-beta) superfamily. BMPs play a crucial role in the development of bones after birth. Their actions are carefully controlled at various levels, including clinical and pre-clinical stages. BMP-2 is utilized in various therapeutic applications, such as root canal procedures, osteoporosis treatment, spinal fusion, non-union fracture management, and bone defect surgery.

BMP is a fundamental part of the treatment for skeletal disorders resulting from degenerative diseases, trauma, or surgical procedures that involve tissue removal. These multifunctional growth factors actively participate in bone formation and maintenance. BMP, one of the most potent growth factors, has the ability to trigger the differentiation of osteoprogenitor cells and mesenchymal stem cells (MSC).

Some of the prominent companies in the Canada bone graft and substitute market are Bioventus LLC, Baxter International Inc, Allosource Inc Plc, etc.

Baxter International Inc manufactures varied healthcare products and services like surgical hemostats, inhaled anesthetics, infusion systems & devices, generic injectable medications, etc. Its products are used in nursing homes, kidney dialysis centers, rehabilitation centers, and hospitals. The company’s goods are distributed through a network of independent distributors, specialty pharmacies, wholesalers, and other alternate site providers and a direct sales staff. It operates in the Americas, Asia-Pacific, Europe, Africa, and the Middle East, with headquarters in Deerfield, Illinois, the United States.